The Ligand Binding Domain of GCNF Is Not Required for Repression of Pluripotency Genes in Mouse Fetal Ovarian Germ Cells
In mice, successful development and reproduction require that all cells, including germ cells, transition from a pluripotent to a differentiated state. This transition is associated with silencing of the pluripotency genes Oct4 and Nanog. Interestingly, these genes are repressed at different develop...
Main Authors: | Okumura, Leah M., Lesch, Bluma J., Page, David C. |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2013
|
Online Access: | http://hdl.handle.net/1721.1/81204 https://orcid.org/0000-0001-9920-3411 |
Similar Items
-
Germ cell nuclear factor is not required for the down-regulation of pluripotency markers in fetal ovarian germ cells
by: Okumura, Leah M
Published: (2013) -
Genetics of germ cell development
by: Lesch, Bluma J., et al.
Published: (2014) -
A set of genes critical to development is epigenetically poised in mouse germ cells from fetal stages through completion of meiosis
by: Lesch, Bluma J., et al.
Published: (2014) -
Erratum: Differential recruitment of methylated CpG binding domains by the orphan receptor GCNF initiates the repression and silencing of Oct4 expression((2009)29:7(1987))
by: Alves, A, et al.
Published: (2009) -
Medaka gcnf is a component of chromatoid body during spermiogenesis
by: Zinan Xie, et al.
Published: (2021-11-01)