Genomic Phenotyping by Barcode Sequencing Broadly Distinguishes between Alkylating Agents, Oxidizing Agents, and Non-Genotoxic Agents, and Reveals a Role for Aromatic Amino Acids in Cellular Recovery after Quinone Exposure

Genomic Phenotyping by Barcode Sequencing Broadly Distinguishes between Alkylating Agents, Oxidizing Agents, and Non-Genotoxic Agents, and Reveals a Role for Aromatic Amino Acids in Cellular Recovery after Quinone Exposure

Toxicity screening of compounds provides a means to identify compounds harmful for human health and the environment. Here, we further develop the technique of genomic phenotyping to improve throughput while maintaining specificity. We exposed cells to eight different compounds that rely on different...

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Váldodahkkit: Svensson, J. Peter, Quirós Pesudo, Laia, McRee, Siobhan K., Adeleye, Yeyejide A., Carmichael, Paul, Quiros Pesudo, Laia, Samson, Leona D
Eará dahkkit: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Materiálatiipa: Artihkal
Giella:en_US
Almmustuhtton: Public Library of Science 2013
Liŋkkat:http://hdl.handle.net/1721.1/81239
https://orcid.org/0000-0002-7112-1454

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http://hdl.handle.net/1721.1/81239
https://orcid.org/0000-0002-7112-1454

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