Cell-Cycle Dependence of Transcription Dominates Noise in Gene Expression
The large variability in mRNA and protein levels found from both static and dynamic measurements in single cells has been largely attributed to random periods of transcription, often occurring in bursts. The cell cycle has a pronounced global role in affecting transcriptional and translational outpu...
Principais autores: | Maheshri, Narendra, Zopf, Christopher John, Quinn, Katie Julia, Zeidman, Joshua A. |
---|---|
Outros Autores: | Massachusetts Institute of Technology. Department of Chemical Engineering |
Formato: | Artigo |
Idioma: | en_US |
Publicado em: |
Public Library of Science
2013
|
Acesso em linha: | http://hdl.handle.net/1721.1/81278 |
Registros relacionados
-
Acquiring Fluorescence Time-lapse Movies of Budding Yeast and Analyzing Single-cell Dynamics using GRAFTS
por: Zopf, Christopher J., et al.
Publicado em: (2014) -
Characterizing cell-cycle as a global regulator of stochastic transcription and noisy gene expression in S. cerevisiae
por: Quinn, Katie J. (Katie Julia)
Publicado em: (2014) -
A regulatory role for repeated decoy transcription factor binding sites in target gene expression
por: Lee, Tek‐Hyung, et al.
Publicado em: (2024) -
A regulatory role for repeated decoy transcription factor binding sites in target gene expression
por: Tek‐Hyung Lee, et al.
Publicado em: (2012-03-01) -
The interaction of promoter chromatin architecture with the cell cycle regulates transcription activation kinetics
por: Zopf, Christopher J. (Christopher John)
Publicado em: (2013)