Cell-Cycle Dependence of Transcription Dominates Noise in Gene Expression

The large variability in mRNA and protein levels found from both static and dynamic measurements in single cells has been largely attributed to random periods of transcription, often occurring in bursts. The cell cycle has a pronounced global role in affecting transcriptional and translational outpu...

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Detalhes bibliográficos
Principais autores: Maheshri, Narendra, Zopf, Christopher John, Quinn, Katie Julia, Zeidman, Joshua A.
Outros Autores: Massachusetts Institute of Technology. Department of Chemical Engineering
Formato: Artigo
Idioma:en_US
Publicado em: Public Library of Science 2013
Acesso em linha:http://hdl.handle.net/1721.1/81278

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