Cell-Cycle Dependence of Transcription Dominates Noise in Gene Expression
The large variability in mRNA and protein levels found from both static and dynamic measurements in single cells has been largely attributed to random periods of transcription, often occurring in bursts. The cell cycle has a pronounced global role in affecting transcriptional and translational outpu...
Main Authors: | Maheshri, Narendra, Zopf, Christopher John, Quinn, Katie Julia, Zeidman, Joshua A. |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemical Engineering |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2013
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Online Access: | http://hdl.handle.net/1721.1/81278 |
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