Barnacle: detecting and characterizing tandem duplications and fusions in transcriptome assemblies

Barnacle: detecting and characterizing tandem duplications and fusions in transcriptome assemblies

Background: Chimeric transcripts, including partial and internal tandem duplications (PTDs, ITDs) and gene fusions, are important in the detection, prognosis, and treatment of human cancers. Results: We describe Barnacle, a production-grade analysis tool that detects such chimeras in de novo asse...

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Bibliographic Details
Main Authors: Swanson, Lucas, Robertson, Gordon, Mungall, Karen L., Butterfield, Yaron S., Chiu, Readman, Corbett, Richard D., Docking, T. R., Hogge, Donna, Jackman, Shaun D., Moore, Richard A., Mungall, Andrew J., Nip, Ka Ming, Parker, Jeremy D. K., Qian, Jenny Q., Raymond, Anthony, Sung, Sandy, Tam, Angela, Thiessen, Nina, Varhol, Richard, Wang, Sherry, Yorukoglu, Deniz, Zhao, YongJun, Hoodless, Pamela A., Sahinalp, S. C., Karsan, Aly, Birol, Inanc, Qian, Jenny, Sahinalp, S.
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:English
Published: BioMed Central Ltd. 2013
Online Access:http://hdl.handle.net/1721.1/81361
https://orcid.org/0000-0003-2315-0768

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