Catalyst-Controlled Chemoselective Arylation of 2-Aminobenzimidazoles
What N would you like? The chemoselective and complementary Pd- and Cu-catalyzed N-arylation of 2-aminobenzimidazoles is described. Selective N-arylation of the amino group was achieved with a Pd-catalyzed method, while selective N-arylation of azole nitrogen was achieved with a Cu-catalyzed procedu...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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Wiley Blackwell
2013
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| Online Access: | http://hdl.handle.net/1721.1/81968 https://orcid.org/0000-0003-3875-4775 |
| _version_ | 1826217476013162496 |
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| author | Ueda, Satoshi Buchwald, Stephen Leffler |
| author2 | Massachusetts Institute of Technology. Department of Chemistry |
| author_facet | Massachusetts Institute of Technology. Department of Chemistry Ueda, Satoshi Buchwald, Stephen Leffler |
| author_sort | Ueda, Satoshi |
| collection | MIT |
| description | What N would you like? The chemoselective and complementary Pd- and Cu-catalyzed N-arylation of 2-aminobenzimidazoles is described. Selective N-arylation of the amino group was achieved with a Pd-catalyzed method, while selective N-arylation of azole nitrogen was achieved with a Cu-catalyzed procedure (see scheme). |
| first_indexed | 2024-09-23T17:04:15Z |
| format | Article |
| id | mit-1721.1/81968 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T17:04:15Z |
| publishDate | 2013 |
| publisher | Wiley Blackwell |
| record_format | dspace |
| spelling | mit-1721.1/819682022-09-29T23:28:07Z Catalyst-Controlled Chemoselective Arylation of 2-Aminobenzimidazoles Ueda, Satoshi Buchwald, Stephen Leffler Massachusetts Institute of Technology. Department of Chemistry Ueda, Satoshi Buchwald, Stephen Leffler What N would you like? The chemoselective and complementary Pd- and Cu-catalyzed N-arylation of 2-aminobenzimidazoles is described. Selective N-arylation of the amino group was achieved with a Pd-catalyzed method, while selective N-arylation of azole nitrogen was achieved with a Cu-catalyzed procedure (see scheme). National Institutes of Health (U.S.) (GM58160) 2013-11-04T15:33:22Z 2013-11-04T15:33:22Z 2012-09 2012-06 Article http://purl.org/eprint/type/JournalArticle 14337851 1521-3773 http://hdl.handle.net/1721.1/81968 Ueda, Satoshi, and Stephen L. Buchwald. “Catalyst-Controlled Chemoselective Arylation of 2-Aminobenzimidazoles.” Angewandte Chemie International Edition 51, no. 41 (October 8, 2012): 10364-10367. https://orcid.org/0000-0003-3875-4775 en_US http://dx.doi.org/10.1002/anie.201204710 Angewandte Chemie International Edition Creative Commons Attribution-Noncommercial-Share Alike 3.0 http://creativecommons.org/licenses/by-nc-sa/3.0/ application/pdf Wiley Blackwell PMC |
| spellingShingle | Ueda, Satoshi Buchwald, Stephen Leffler Catalyst-Controlled Chemoselective Arylation of 2-Aminobenzimidazoles |
| title | Catalyst-Controlled Chemoselective Arylation of 2-Aminobenzimidazoles |
| title_full | Catalyst-Controlled Chemoselective Arylation of 2-Aminobenzimidazoles |
| title_fullStr | Catalyst-Controlled Chemoselective Arylation of 2-Aminobenzimidazoles |
| title_full_unstemmed | Catalyst-Controlled Chemoselective Arylation of 2-Aminobenzimidazoles |
| title_short | Catalyst-Controlled Chemoselective Arylation of 2-Aminobenzimidazoles |
| title_sort | catalyst controlled chemoselective arylation of 2 aminobenzimidazoles |
| url | http://hdl.handle.net/1721.1/81968 https://orcid.org/0000-0003-3875-4775 |
| work_keys_str_mv | AT uedasatoshi catalystcontrolledchemoselectivearylationof2aminobenzimidazoles AT buchwaldstephenleffler catalystcontrolledchemoselectivearylationof2aminobenzimidazoles |