Alkyl-Alkyl Suzuki Cross-Coupling of Unactivated Secondary Alkyl Chlorides
No such thing as a problem substrate! In a reaction designed specifically for the title substrates C-C coupling with alkyl boranes occurred in good yield at room temperature with commercially available catalyst components (see scheme). This versatile method is also suitable for Suzuki reactions of s...
| Główni autorzy: | , |
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| Format: | Artykuł |
| Język: | en_US |
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Wiley Blackwell
2013
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| Dostęp online: | http://hdl.handle.net/1721.1/82045 |
| _version_ | 1826202741663334400 |
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| author | Lu, Zhe Fu, Gregory C. |
| author2 | Massachusetts Institute of Technology. Department of Chemistry |
| author_facet | Massachusetts Institute of Technology. Department of Chemistry Lu, Zhe Fu, Gregory C. |
| author_sort | Lu, Zhe |
| collection | MIT |
| description | No such thing as a problem substrate! In a reaction designed specifically for the title substrates C-C coupling with alkyl boranes occurred in good yield at room temperature with commercially available catalyst components (see scheme). This versatile method is also suitable for Suzuki reactions of secondary and primary alkyl bromides and iodides, as well as primary alkyl chlorides. |
| first_indexed | 2024-09-23T12:15:51Z |
| format | Article |
| id | mit-1721.1/82045 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T12:15:51Z |
| publishDate | 2013 |
| publisher | Wiley Blackwell |
| record_format | dspace |
| spelling | mit-1721.1/820452022-10-01T08:50:06Z Alkyl-Alkyl Suzuki Cross-Coupling of Unactivated Secondary Alkyl Chlorides Lu, Zhe Fu, Gregory C. Massachusetts Institute of Technology. Department of Chemistry Lu, Zhe Fu, Gregory C. No such thing as a problem substrate! In a reaction designed specifically for the title substrates C-C coupling with alkyl boranes occurred in good yield at room temperature with commercially available catalyst components (see scheme). This versatile method is also suitable for Suzuki reactions of secondary and primary alkyl bromides and iodides, as well as primary alkyl chlorides. National Institute of General Medical Sciences (U.S.) (Grant R01-GM62871) Eli Lilly and Company (Fellowship) Martin Family Society of Fellows for Sustainability (Fellowship) Merck Research Laboratories Novartis (Firm) 2013-11-08T15:27:18Z 2013-11-08T15:27:18Z 2010-08 2010-05 Article http://purl.org/eprint/type/JournalArticle 14337851 1521-3773 http://hdl.handle.net/1721.1/82045 Lu, Zhe, and Gregory C. Fu. “Alkyl-Alkyl Suzuki Cross-Coupling of Unactivated Secondary Alkyl Chlorides.” Angewandte Chemie International Edition 49, no. 37 (September 3, 2010): 6676-6678. en_US http://dx.doi.org/10.1002/anie.201003272 Angewandte Chemie International Edition Creative Commons Attribution-Noncommercial-Share Alike 3.0 http://creativecommons.org/licenses/by-nc-sa/3.0/ application/pdf Wiley Blackwell PMC |
| spellingShingle | Lu, Zhe Fu, Gregory C. Alkyl-Alkyl Suzuki Cross-Coupling of Unactivated Secondary Alkyl Chlorides |
| title | Alkyl-Alkyl Suzuki Cross-Coupling of Unactivated Secondary Alkyl Chlorides |
| title_full | Alkyl-Alkyl Suzuki Cross-Coupling of Unactivated Secondary Alkyl Chlorides |
| title_fullStr | Alkyl-Alkyl Suzuki Cross-Coupling of Unactivated Secondary Alkyl Chlorides |
| title_full_unstemmed | Alkyl-Alkyl Suzuki Cross-Coupling of Unactivated Secondary Alkyl Chlorides |
| title_short | Alkyl-Alkyl Suzuki Cross-Coupling of Unactivated Secondary Alkyl Chlorides |
| title_sort | alkyl alkyl suzuki cross coupling of unactivated secondary alkyl chlorides |
| url | http://hdl.handle.net/1721.1/82045 |
| work_keys_str_mv | AT luzhe alkylalkylsuzukicrosscouplingofunactivatedsecondaryalkylchlorides AT fugregoryc alkylalkylsuzukicrosscouplingofunactivatedsecondaryalkylchlorides |