Negishi Coupling of Secondary Alkylzinc Halides with Aryl Bromides and Chlorides
An efficient palladium-catalyzed process has been developed for Negishi coupling of secondary alkylzinc halides with a wide range of aryl bromides and activated aryl chlorides. A palladium catalyst composed of a new biaryldialkylphosphine ligand, CPhos, effectively promotes the rate of the reductive...
Main Authors: | Han, Chong, Buchwald, Stephen Leffler |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society (ACS)
2013
|
Online Access: | http://hdl.handle.net/1721.1/82067 https://orcid.org/0000-0003-3875-4775 |
Similar Items
-
Nickel-Catalyzed Asymmetric Negishi Cross-Couplings of Racemic Secondary Allylic Chlorides with Alkylzincs
by: Lou, Sha, et al.
Published: (2011) -
Highly Selective Palladium-Catalyzed Cross-Coupling of Secondary Alkylzinc Reagents with Heteroaryl Halides
by: Yang, Yang, et al.
Published: (2015) -
Palladium-Catalyzed Completely Linear-Selective Negishi Cross-Coupling of Allylzinc Halides with Aryl and Vinyl Electrophiles
by: Yang, Yang, et al.
Published: (2015) -
Catalytic Enantioselective Cross-Couplings of Secondary Alkyl Electrophiles with Secondary Alkylmetal Nucleophiles: Negishi Reactions of Racemic Benzylic Bromides with Achiral Alkylzinc Reagents
by: Cordier, Christopher J., et al.
Published: (2013) -
Palladium-Catalyzed Conversion of Aryl and Vinyl Triflates to Bromides and Chlorides
by: Shen, Xiaoqiang, et al.
Published: (2012)