Functionalized Templates for the Convergent Assembly of Polyethers: Synthesis of the HIJK Rings of Gymnocin A

Extension ladder: The successful application of epoxide-opening strategies towards the synthesis of ladder-type polyethers is contingent upon further elaboration of the product. By employing two different functionalized templates, a fragment of gymnocin A that bears four sites for subsequent fragmen...

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Main Authors: Van Dyke, Aaron R., Jamison, Timothy F.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: Wiley Blackwell 2013
Online Access:http://hdl.handle.net/1721.1/82096
https://orcid.org/0000-0002-8601-7799
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author Van Dyke, Aaron R.
Jamison, Timothy F.
author2 Massachusetts Institute of Technology. Department of Chemistry
author_facet Massachusetts Institute of Technology. Department of Chemistry
Van Dyke, Aaron R.
Jamison, Timothy F.
author_sort Van Dyke, Aaron R.
collection MIT
description Extension ladder: The successful application of epoxide-opening strategies towards the synthesis of ladder-type polyethers is contingent upon further elaboration of the product. By employing two different functionalized templates, a fragment of gymnocin A that bears four sites for subsequent fragment coupling has been prepared (see scheme; Bn=benzyl).
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spelling mit-1721.1/820962022-10-01T04:55:37Z Functionalized Templates for the Convergent Assembly of Polyethers: Synthesis of the HIJK Rings of Gymnocin A Van Dyke, Aaron R. Jamison, Timothy F. Massachusetts Institute of Technology. Department of Chemistry Van Dyke, Aaron R. Jamison, Timothy F. Extension ladder: The successful application of epoxide-opening strategies towards the synthesis of ladder-type polyethers is contingent upon further elaboration of the product. By employing two different functionalized templates, a fragment of gymnocin A that bears four sites for subsequent fragment coupling has been prepared (see scheme; Bn=benzyl). National Institute of General Medical Sciences (U.S.) (GM72566) Wyeth Research (Fellowship) 2013-11-13T14:29:18Z 2013-11-13T14:29:18Z 2009-05 2009-01 Article http://purl.org/eprint/type/JournalArticle 14337851 15213773 http://hdl.handle.net/1721.1/82096 Van Dyke, Aaron R., and Timothy F. Jamison. “Functionalized Templates for the Convergent Assembly of Polyethers: Synthesis of the HIJK Rings of Gymnocin A.” Angewandte Chemie International Edition 48, no. 24 (June 2, 2009): 4430-4432. https://orcid.org/0000-0002-8601-7799 en_US http://dx.doi.org/10.1002/anie.200900924 Angewandte Chemie International Edition Creative Commons Attribution-Noncommercial-Share Alike 3.0 http://creativecommons.org/licenses/by-nc-sa/3.0/ application/pdf Wiley Blackwell PMC
spellingShingle Van Dyke, Aaron R.
Jamison, Timothy F.
Functionalized Templates for the Convergent Assembly of Polyethers: Synthesis of the HIJK Rings of Gymnocin A
title Functionalized Templates for the Convergent Assembly of Polyethers: Synthesis of the HIJK Rings of Gymnocin A
title_full Functionalized Templates for the Convergent Assembly of Polyethers: Synthesis of the HIJK Rings of Gymnocin A
title_fullStr Functionalized Templates for the Convergent Assembly of Polyethers: Synthesis of the HIJK Rings of Gymnocin A
title_full_unstemmed Functionalized Templates for the Convergent Assembly of Polyethers: Synthesis of the HIJK Rings of Gymnocin A
title_short Functionalized Templates for the Convergent Assembly of Polyethers: Synthesis of the HIJK Rings of Gymnocin A
title_sort functionalized templates for the convergent assembly of polyethers synthesis of the hijk rings of gymnocin a
url http://hdl.handle.net/1721.1/82096
https://orcid.org/0000-0002-8601-7799
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