An Efficient Process for Pd-Catalyzed C−N Cross-Coupling Reactions of Aryl Iodides: Insight Into Controlling Factors

An investigation into Pd-catalyzed C−N cross-coupling reactions of aryl iodides is described. NaI is shown to have a significant inhibitory effect on these processes. By switching to a solvent system in which the iodide byproduct was insoluble, reactions of aryl iodides were accomplished with the sa...

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Bibliographic Details
Main Authors: Fors, Brett P., Buchwald, Stephen Leffler, Davis, Nicole Rose
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2013
Online Access:http://hdl.handle.net/1721.1/82102
https://orcid.org/0000-0003-3875-4775

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