Transimination of Quinone Imines: A Mechanism for Embedding Exogenous Redox Activity into the Nucleosome
Aminophenols can redox cycle through the corresponding quinone imines to generate ROS. The electrophilic quinone imine intermediate can react with protein thiols as a mechanism of immobilization in vivo. Here, we describe the previously unkown transimination of a quinone imine by lysine as an altern...
| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
American Chemical Society (ACS)
2013
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| Online Access: | http://hdl.handle.net/1721.1/82110 https://orcid.org/0000-0001-6774-9639 https://orcid.org/0000-0003-0771-9889 |