Catalytic Addition of Simple Alkenes to Carbonyl Compounds by Use of Group 10 Metals
Recent advances using nickel complexes in the activation of unactivated monosubstituted olefins for catalytic intermolecular carbon-carbon bond-forming reactions with carbonyl compounds, such as simple aldehydes, isocyanates, and conjugated aldehydes and ketones, are discussed. In these reactions, t...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | en_US |
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Thieme Publishing Group
2013
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| Online Access: | http://hdl.handle.net/1721.1/82119 https://orcid.org/0000-0002-8601-7799 |
| _version_ | 1826213358849753088 |
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| author | Ho, Chun-Yu Chan, Chun-Wa Schleicher, Kristin D. Jamison, Timothy F. |
| author2 | Massachusetts Institute of Technology. Department of Chemistry |
| author_facet | Massachusetts Institute of Technology. Department of Chemistry Ho, Chun-Yu Chan, Chun-Wa Schleicher, Kristin D. Jamison, Timothy F. |
| author_sort | Ho, Chun-Yu |
| collection | MIT |
| description | Recent advances using nickel complexes in the activation of unactivated monosubstituted olefins for catalytic intermolecular carbon-carbon bond-forming reactions with carbonyl compounds, such as simple aldehydes, isocyanates, and conjugated aldehydes and ketones, are discussed. In these reactions, the olefins function as vinyl- and allylmetal equivalents, providing a new strategy for organic synthesis. Current limitations and the outlook for this new strategy are also discussed. |
| first_indexed | 2024-09-23T15:47:50Z |
| format | Article |
| id | mit-1721.1/82119 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T15:47:50Z |
| publishDate | 2013 |
| publisher | Thieme Publishing Group |
| record_format | dspace |
| spelling | mit-1721.1/821192022-10-02T04:08:22Z Catalytic Addition of Simple Alkenes to Carbonyl Compounds by Use of Group 10 Metals Ho, Chun-Yu Chan, Chun-Wa Schleicher, Kristin D. Jamison, Timothy F. Massachusetts Institute of Technology. Department of Chemistry Schleicher, Kristin D. Jamison, Timothy F. Recent advances using nickel complexes in the activation of unactivated monosubstituted olefins for catalytic intermolecular carbon-carbon bond-forming reactions with carbonyl compounds, such as simple aldehydes, isocyanates, and conjugated aldehydes and ketones, are discussed. In these reactions, the olefins function as vinyl- and allylmetal equivalents, providing a new strategy for organic synthesis. Current limitations and the outlook for this new strategy are also discussed. National Institute of General Medical Sciences (U.S.) (GM-063775) National Institute of General Medical Sciences (U.S.) (GM-072566) National Science Foundation (U.S.) (CAREER CHE-0134704) Amgen Inc. Boehringer Ingelheim Pharmaceuticals Bristol-Myers Squibb Company Merck & Co., Inc. GlaxoSmithKline Johnson & Johnson Pfizer Inc. Alfred P. Sloan Foundation Wyeth Research Deshpande Center for Technological Innovation National Science Foundation (U.S.) (CHE-9809061) National Science Foundation (U.S.) (DBI-9729592) National Institutes of Health (U.S.) (1S10RR13886-01) 2013-11-15T15:25:49Z 2013-11-15T15:25:49Z 2009-09 2009-03 Article http://purl.org/eprint/type/JournalArticle 0936-5214 1437-2096 http://hdl.handle.net/1721.1/82119 Ho, Chun-Yu, Kristin Schleicher, Chun-Wa Chan, and Timothy Jamison. “Catalytic Addition of Simple Alkenes to Carbonyl Compounds by Use of Group 10 Metals.” Synlett 2009, no. 16 (October 4, 2009): 2565-2582. https://orcid.org/0000-0002-8601-7799 en_US http://dx.doi.org/10.1055/s-0029-1217747 Synlett Creative Commons Attribution-Noncommercial-Share Alike 3.0 http://creativecommons.org/licenses/by-nc-sa/3.0/ application/pdf Thieme Publishing Group PMC |
| spellingShingle | Ho, Chun-Yu Chan, Chun-Wa Schleicher, Kristin D. Jamison, Timothy F. Catalytic Addition of Simple Alkenes to Carbonyl Compounds by Use of Group 10 Metals |
| title | Catalytic Addition of Simple Alkenes to Carbonyl Compounds by Use of Group 10 Metals |
| title_full | Catalytic Addition of Simple Alkenes to Carbonyl Compounds by Use of Group 10 Metals |
| title_fullStr | Catalytic Addition of Simple Alkenes to Carbonyl Compounds by Use of Group 10 Metals |
| title_full_unstemmed | Catalytic Addition of Simple Alkenes to Carbonyl Compounds by Use of Group 10 Metals |
| title_short | Catalytic Addition of Simple Alkenes to Carbonyl Compounds by Use of Group 10 Metals |
| title_sort | catalytic addition of simple alkenes to carbonyl compounds by use of group 10 metals |
| url | http://hdl.handle.net/1721.1/82119 https://orcid.org/0000-0002-8601-7799 |
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