The development of endo-selective epoxide-opening cascades in water

This tutorial review traces the development of endo-regioselective epoxide-opening reactions in water. Templated, water-promoted epoxide-opening cyclization reactions can offer rapid access to subunits of the ladder polyethers, a fascinating and complex family of natural products. This review may be...

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Main Authors: Morten, Christopher J., Byers, Jeffery A., Van Dyke, Aaron R., Vilotijevic, Ivan, Jamison, Timothy F.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: Royal Society of Chemistry, The 2013
Online Access:http://hdl.handle.net/1721.1/82125
https://orcid.org/0000-0002-8601-7799
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author Morten, Christopher J.
Byers, Jeffery A.
Van Dyke, Aaron R.
Vilotijevic, Ivan
Jamison, Timothy F.
author2 Massachusetts Institute of Technology. Department of Chemistry
author_facet Massachusetts Institute of Technology. Department of Chemistry
Morten, Christopher J.
Byers, Jeffery A.
Van Dyke, Aaron R.
Vilotijevic, Ivan
Jamison, Timothy F.
author_sort Morten, Christopher J.
collection MIT
description This tutorial review traces the development of endo-regioselective epoxide-opening reactions in water. Templated, water-promoted epoxide-opening cyclization reactions can offer rapid access to subunits of the ladder polyethers, a fascinating and complex family of natural products. This review may be of interest to those curious about the ladder polyethers and their hypothesized biogenesis, about organic reactions in water, and about the development and application of cascade reactions in organic synthesis.
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spelling mit-1721.1/821252022-09-28T08:28:33Z The development of endo-selective epoxide-opening cascades in water Morten, Christopher J. Byers, Jeffery A. Van Dyke, Aaron R. Vilotijevic, Ivan Jamison, Timothy F. Massachusetts Institute of Technology. Department of Chemistry Morten, Christopher J. Byers, Jeffery A. Van Dyke, Aaron R. Vilotijevic, Ivan Jamison, Timothy F. This tutorial review traces the development of endo-regioselective epoxide-opening reactions in water. Templated, water-promoted epoxide-opening cyclization reactions can offer rapid access to subunits of the ladder polyethers, a fascinating and complex family of natural products. This review may be of interest to those curious about the ladder polyethers and their hypothesized biogenesis, about organic reactions in water, and about the development and application of cascade reactions in organic synthesis. 2013-11-15T16:47:39Z 2013-11-15T16:47:39Z 2009-09 2009-06 Article http://purl.org/eprint/type/JournalArticle 0306-0012 1460-4744 http://hdl.handle.net/1721.1/82125 Morten, Christopher J., Jeffery A. Byers, Aaron R. Van Dyke, Ivan Vilotijevic, and Timothy F. Jamison. “The development of endo-selective epoxide-opening cascades in water.” Chemical Society Reviews 38, no. 11 (2009): 3175. https://orcid.org/0000-0002-8601-7799 en_US http://dx.doi.org/10.1039/b816697h Chemical Society Reviews Creative Commons Attribution-Noncommercial-Share Alike 3.0 http://creativecommons.org/licenses/by-nc-sa/3.0/ application/pdf Royal Society of Chemistry, The PMC
spellingShingle Morten, Christopher J.
Byers, Jeffery A.
Van Dyke, Aaron R.
Vilotijevic, Ivan
Jamison, Timothy F.
The development of endo-selective epoxide-opening cascades in water
title The development of endo-selective epoxide-opening cascades in water
title_full The development of endo-selective epoxide-opening cascades in water
title_fullStr The development of endo-selective epoxide-opening cascades in water
title_full_unstemmed The development of endo-selective epoxide-opening cascades in water
title_short The development of endo-selective epoxide-opening cascades in water
title_sort development of endo selective epoxide opening cascades in water
url http://hdl.handle.net/1721.1/82125
https://orcid.org/0000-0002-8601-7799
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