Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable site

Replacement of a single dA nucleotide positioned at a programmed site in a DNA plasmid with its 7-deaza-analog is described together with its complete resistance to restriction enzymatic cleavage.

Bibliographic Details
Main Authors: Ang, Wee Han, Lippard, Stephen J.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: Royal Society of Chemistry 2013
Online Access:http://hdl.handle.net/1721.1/82139
https://orcid.org/0000-0002-2693-4982
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author Ang, Wee Han
Lippard, Stephen J.
author2 Massachusetts Institute of Technology. Department of Chemistry
author_facet Massachusetts Institute of Technology. Department of Chemistry
Ang, Wee Han
Lippard, Stephen J.
author_sort Ang, Wee Han
collection MIT
description Replacement of a single dA nucleotide positioned at a programmed site in a DNA plasmid with its 7-deaza-analog is described together with its complete resistance to restriction enzymatic cleavage.
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spelling mit-1721.1/821392022-09-29T10:01:01Z Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable site Ang, Wee Han Lippard, Stephen J. Massachusetts Institute of Technology. Department of Chemistry Ang, Wee Han Lippard, Stephen J. Replacement of a single dA nucleotide positioned at a programmed site in a DNA plasmid with its 7-deaza-analog is described together with its complete resistance to restriction enzymatic cleavage. National Cancer Institute (U.S.) (Grant CA34992) 2013-11-15T19:04:17Z 2013-11-15T19:04:17Z 2009-09 2009-07 Article http://purl.org/eprint/type/JournalArticle 1359-7345 1364-548X http://hdl.handle.net/1721.1/82139 Ang, Wee Han, and Stephen J. Lippard. “Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable site.” Chemical Communications, no. 39 (2009): 5820. https://orcid.org/0000-0002-2693-4982 en_US http://dx.doi.org/10.1039/b914843d Chemical Communications Creative Commons Attribution-Noncommercial-Share Alike 3.0 http://creativecommons.org/licenses/by-nc-sa/3.0/ application/pdf Royal Society of Chemistry PMC
spellingShingle Ang, Wee Han
Lippard, Stephen J.
Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable site
title Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable site
title_full Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable site
title_fullStr Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable site
title_full_unstemmed Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable site
title_short Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable site
title_sort functional consequence of plasmid dna modified site specifically with 7 deaza deoxyadenosine at a single programmable site
url http://hdl.handle.net/1721.1/82139
https://orcid.org/0000-0002-2693-4982
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