Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable site
Replacement of a single dA nucleotide positioned at a programmed site in a DNA plasmid with its 7-deaza-analog is described together with its complete resistance to restriction enzymatic cleavage.
Main Authors: | Ang, Wee Han, Lippard, Stephen J. |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | en_US |
Published: |
Royal Society of Chemistry
2013
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Online Access: | http://hdl.handle.net/1721.1/82139 https://orcid.org/0000-0002-2693-4982 |
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