Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable site
Replacement of a single dA nucleotide positioned at a programmed site in a DNA plasmid with its 7-deaza-analog is described together with its complete resistance to restriction enzymatic cleavage.
Main Authors: | Ang, Wee Han, Lippard, Stephen J. |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | en_US |
Published: |
Royal Society of Chemistry
2013
|
Online Access: | http://hdl.handle.net/1721.1/82139 https://orcid.org/0000-0002-2693-4982 |
Similar Items
-
Preparation of Mammalian Expression Vectors Incorporating Site-Specifically Platinated-DNA Lesions
by: Ang, Wee Han, et al.
Published: (2013) -
Production of recombinant p53 protein by PCR-based site directed mutagenesis of plasmid DNA
by: Bakhtiar, M. Taher, et al.
Published: (2010) -
mwr Xer site-specific recombination is hypersensitive to DNA supercoiling.
by: Trigueros, S, et al.
Published: (2009) -
Bromo-deaza-SAH: a potent and selective DOT1L inhibitor.
by: Yu, W, et al.
Published: (2013) -
Studies on the site-specific self cleavage of G-quadruplexes and the topological properties of DNA
by: Hiew, Shu Hui
Published: (2012)