Non-traditional platinum compounds for improved accumulation, oral bioavailability, and tumor targeting
The five platinum anticancer compounds currently in clinical use conform to structure–activity relationships formulated (M. J. Cleare and J. D. Hoeschele, Bioinorg. Chem., 1973, 2, 187–210) shortly after the discovery that cis-diamminedichloroplatinum(II), cisplatin, has antitumor activity in mice....
| Main Authors: | , |
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| Format: | Article |
| Language: | en_US |
| Published: |
Royal Society of Chemistry, The
2013
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| Online Access: | http://hdl.handle.net/1721.1/82144 https://orcid.org/0000-0002-2693-4982 |