Lysosomal Trafficking, Antigen Presentation, and Microbial Killing Are Controlled by the Arf-like GTPase Arl8b

Lysosomal Trafficking, Antigen Presentation, and Microbial Killing Are Controlled by the Arf-like GTPase Arl8b

Antigen presentation and microbial killing are critical arms of host defense that depend upon cargo trafficking into lysosomes. Yet, the molecular regulators of traffic into lysosomes are only partly understood. Here, using a lysosome-dependent immunological screen of a trafficking shRNA library, we...

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Bibliographic Details
Main Authors: Garg, Salil, Sharma, Mahak, Ung, Cindy, Tuli, Amit, Barral, Duarte C., Hava, David L., Veerapen, Natacha, Besra, Gurdyal S., Hacohen, Nir, Brenner, Michael B.
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:en_US
Published: Elsevier 2013
Online Access:http://hdl.handle.net/1721.1/82158

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