Molecular Basis for Specific Regulation of Neuronal Kinesin-3 Motors by Doublecortin Family Proteins

Molecular Basis for Specific Regulation of Neuronal Kinesin-3 Motors by Doublecortin Family Proteins

Doublecortin (Dcx) defines a growing family of microtubule (MT)-associated proteins (MAPs) involved in neuronal migration and process outgrowth. We show that Dcx is essential for the function of Kif1a, a kinesin-3 motor protein that traffics synaptic vesicles. Neurons lacking Dcx and/or its structur...

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Bibliographic Details
Main Authors: Liu, Judy S., Schubert, Christian R., Fu, Xiaoqin, Fourniol, Franck J., Jaiswal, Jyoti K., Houdusse, Anne, Stultz, Collin M., Moores, Carolyn A., Walsh, Christopher A., Schubert, Christian R., Stultz, Collin M.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Elsevier 2013
Online Access:http://hdl.handle.net/1721.1/82159
https://orcid.org/0000-0002-3415-242X

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