Development and study of synthetic polypeptides for biomaterial applications
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2013.
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| Other Authors: | |
| Format: | Thesis |
| Language: | eng |
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Massachusetts Institute of Technology
2013
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| Online Access: | http://hdl.handle.net/1721.1/82333 |
| _version_ | 1826210789623595008 |
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| author | Morey, Shannon Marie |
| author2 | Paula T. Hammond. |
| author_facet | Paula T. Hammond. Morey, Shannon Marie |
| author_sort | Morey, Shannon Marie |
| collection | MIT |
| description | Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2013. |
| first_indexed | 2024-09-23T14:55:45Z |
| format | Thesis |
| id | mit-1721.1/82333 |
| institution | Massachusetts Institute of Technology |
| language | eng |
| last_indexed | 2024-09-23T14:55:45Z |
| publishDate | 2013 |
| publisher | Massachusetts Institute of Technology |
| record_format | dspace |
| spelling | mit-1721.1/823332019-04-10T17:50:24Z Development and study of synthetic polypeptides for biomaterial applications Morey, Shannon Marie Paula T. Hammond. Massachusetts Institute of Technology. Department of Chemistry. Massachusetts Institute of Technology. Department of Chemistry. Chemistry. Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2013. Vita. Cataloged from PDF version of thesis. Includes bibliographical references (p. 38-39). Creating new scaffolds for cells is critical to the development of new tissue engineering techniques. In this work, the synthesis of new polypeptide systems is discussed. These systems are intended for the formation of hydrogels which can then be used as cell substrates. Attempts at using the clickable synthetic polypeptide poly(ypropargyl L-glutamate) (PPLG) to form a self-assembly amphiphilic system is discussed, as is the formation of potentially amphiphilic block copolymers with PPLG. The synthesis of a hydrolytically stable synthetic polypeptide with click functionality is also investigated. Additionally, the creation of a polypeptide system with two functionalities available for orthogonal click chemistry is discussed. by Shannon Marie Morey. S.M. 2013-11-18T19:10:04Z 2013-11-18T19:10:04Z 2013 2013 Thesis http://hdl.handle.net/1721.1/82333 861621344 eng M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 39 p. application/pdf Massachusetts Institute of Technology |
| spellingShingle | Chemistry. Morey, Shannon Marie Development and study of synthetic polypeptides for biomaterial applications |
| title | Development and study of synthetic polypeptides for biomaterial applications |
| title_full | Development and study of synthetic polypeptides for biomaterial applications |
| title_fullStr | Development and study of synthetic polypeptides for biomaterial applications |
| title_full_unstemmed | Development and study of synthetic polypeptides for biomaterial applications |
| title_short | Development and study of synthetic polypeptides for biomaterial applications |
| title_sort | development and study of synthetic polypeptides for biomaterial applications |
| topic | Chemistry. |
| url | http://hdl.handle.net/1721.1/82333 |
| work_keys_str_mv | AT moreyshannonmarie developmentandstudyofsyntheticpolypeptidesforbiomaterialapplications |