DNA Self-Assembly of Targeted Near-Infrared-Responsive Gold Nanoparticles for Cancer Thermo-Chemotherapy
Targeted cancer therapy: Inspired by the ability of DNA hybridization, a targeted near-infrared (NIR) light-responsive delivery system has been developed through simple DNA self-assembly (see picture; PEG=polyethylene glycol). This DNA-based platform shows the ability of releasing therapeutics upon...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | en_US |
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Wiley Blackwell
2013
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| Online Access: | http://hdl.handle.net/1721.1/82885 https://orcid.org/0000-0001-6518-0311 https://orcid.org/0000-0002-2640-3006 |
| _version_ | 1826190938466156544 |
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| author | Xiao, Zeyu Ji, Changwei Shi, Jinjun Frieder, Jillian Wu, Jun Farokhzad, Omid C. Shi, JinJun Pridgen, Eric M. |
| author2 | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
| author_facet | Massachusetts Institute of Technology. Institute for Medical Engineering & Science Xiao, Zeyu Ji, Changwei Shi, Jinjun Frieder, Jillian Wu, Jun Farokhzad, Omid C. Shi, JinJun Pridgen, Eric M. |
| author_sort | Xiao, Zeyu |
| collection | MIT |
| description | Targeted cancer therapy: Inspired by the ability of DNA hybridization, a targeted near-infrared (NIR) light-responsive delivery system has been developed through simple DNA self-assembly (see picture; PEG=polyethylene glycol). This DNA-based platform shows the ability of releasing therapeutics upon near-infrared irradiation, and remarkable targeted thermo- and chemotherapeutic efficacy in vitro and in vivo. |
| first_indexed | 2024-09-23T08:47:36Z |
| format | Article |
| id | mit-1721.1/82885 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T08:47:36Z |
| publishDate | 2013 |
| publisher | Wiley Blackwell |
| record_format | dspace |
| spelling | mit-1721.1/828852022-09-30T11:17:19Z DNA Self-Assembly of Targeted Near-Infrared-Responsive Gold Nanoparticles for Cancer Thermo-Chemotherapy Xiao, Zeyu Ji, Changwei Shi, Jinjun Frieder, Jillian Wu, Jun Farokhzad, Omid C. Shi, JinJun Pridgen, Eric M. Massachusetts Institute of Technology. Institute for Medical Engineering & Science MIT-Harvard Center for Cancer Nanotechnology Excellence Massachusetts Institute of Technology. Department of Chemical Engineering Koch Institute for Integrative Cancer Research at MIT Shi, JinJun Pridgen, Eric Michael Wu, Jun Farokhzad, Omid C. Targeted cancer therapy: Inspired by the ability of DNA hybridization, a targeted near-infrared (NIR) light-responsive delivery system has been developed through simple DNA self-assembly (see picture; PEG=polyethylene glycol). This DNA-based platform shows the ability of releasing therapeutics upon near-infrared irradiation, and remarkable targeted thermo- and chemotherapeutic efficacy in vitro and in vivo. National Institutes of Health (U.S.) (Grant CA151884) Prostate Cancer Foundation (Program in Cancer Nanotherapeutics) 2013-12-09T15:26:30Z 2013-12-09T15:26:30Z 2012-10 2012-09 Article http://purl.org/eprint/type/JournalArticle 14337851 1521-3773 http://hdl.handle.net/1721.1/82885 Xiao, Zeyu, Changwei Ji, Jinjun Shi, Eric M. Pridgen, Jillian Frieder, Jun Wu, and Omid C. Farokhzad. “DNA Self-Assembly of Targeted Near-Infrared-Responsive Gold Nanoparticles for Cancer Thermo-Chemotherapy.” Angewandte Chemie International Edition 51, no. 47 (November 19, 2012): 11853-11857. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim https://orcid.org/0000-0001-6518-0311 https://orcid.org/0000-0002-2640-3006 en_US http://dx.doi.org/10.1002/anie.201204018 Angewandte Chemie International Edition http://creativecommons.org/licenses/by/2.5/ application/pdf Wiley Blackwell PMC |
| spellingShingle | Xiao, Zeyu Ji, Changwei Shi, Jinjun Frieder, Jillian Wu, Jun Farokhzad, Omid C. Shi, JinJun Pridgen, Eric M. DNA Self-Assembly of Targeted Near-Infrared-Responsive Gold Nanoparticles for Cancer Thermo-Chemotherapy |
| title | DNA Self-Assembly of Targeted Near-Infrared-Responsive Gold Nanoparticles for Cancer Thermo-Chemotherapy |
| title_full | DNA Self-Assembly of Targeted Near-Infrared-Responsive Gold Nanoparticles for Cancer Thermo-Chemotherapy |
| title_fullStr | DNA Self-Assembly of Targeted Near-Infrared-Responsive Gold Nanoparticles for Cancer Thermo-Chemotherapy |
| title_full_unstemmed | DNA Self-Assembly of Targeted Near-Infrared-Responsive Gold Nanoparticles for Cancer Thermo-Chemotherapy |
| title_short | DNA Self-Assembly of Targeted Near-Infrared-Responsive Gold Nanoparticles for Cancer Thermo-Chemotherapy |
| title_sort | dna self assembly of targeted near infrared responsive gold nanoparticles for cancer thermo chemotherapy |
| url | http://hdl.handle.net/1721.1/82885 https://orcid.org/0000-0001-6518-0311 https://orcid.org/0000-0002-2640-3006 |
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