The structural basis of RNA-catalyzed RNA polymerization
Early life presumably required polymerase ribozymes capable of replicating RNA. Known polymerase ribozymes best approximating such replicases use as their catalytic engine an RNA-ligase ribozyme originally selected from random RNA sequences. Here we report 3.15-Å crystal structures of this ligase tr...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Elsevier B.V.
2014
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| Online Access: | http://hdl.handle.net/1721.1/83621 https://orcid.org/0000-0002-3872-2856 |