Combining Genotype Improvement and Statistical Media Optimization for Isoprenoid Production in E. coli
Isoprenoids are a large and diverse class of compounds that includes many high value natural products and are thus in great demand. To meet the increasing demand for isoprenoid compounds, metabolic engineering of microbes has been used to produce isoprenoids in an economical and sustainable manner....
Main Authors: | Zhang, Congqiang, Chen, Xixian, Zou, Ruiyang, Zhou, Kang, Stephanopoulos, Gregory, Too, Heng-Phon |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemical Engineering |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2014
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Online Access: | http://hdl.handle.net/1721.1/83863 https://orcid.org/0000-0001-6909-4568 |
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