Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

The epithelial-to-mesenchymal transition (EMT) produces cancer cells that are invasive, migratory, and exhibit stem cell characteristics, hallmarks of cells that have the potential to generate metastases. Inducers of the EMT include several transcription factors (TFs), such as Goosecoid, Snail, and...

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Bibliographic Details
Main Authors: Taube, Joseph H., Herschkowitz, Jason I., Komurov, Kakajan, Zhou, Alicia Y., Gupta, Supriya, Yang, Jing, Hartwell, Kimberly A., Gupta, Piyush, Evans, Kurt W., Hollier, Brett G., Ram, Prahlad T., Rosen, Jeffrey M., Mani, Sendurai A., Onder, Tamer T, Lander, Eric Steven, Weinberg, Robert A
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2014
Online Access:http://hdl.handle.net/1721.1/84510
https://orcid.org/0000-0002-0895-3557
https://orcid.org/0000-0002-9703-1780

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