Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
The epithelial-to-mesenchymal transition (EMT) produces cancer cells that are invasive, migratory, and exhibit stem cell characteristics, hallmarks of cells that have the potential to generate metastases. Inducers of the EMT include several transcription factors (TFs), such as Goosecoid, Snail, and...
Main Authors: | Taube, Joseph H., Herschkowitz, Jason I., Komurov, Kakajan, Zhou, Alicia Y., Gupta, Supriya, Yang, Jing, Hartwell, Kimberly A., Gupta, Piyush, Evans, Kurt W., Hollier, Brett G., Ram, Prahlad T., Rosen, Jeffrey M., Mani, Sendurai A., Onder, Tamer T, Lander, Eric Steven, Weinberg, Robert A |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2014
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Online Access: | http://hdl.handle.net/1721.1/84510 https://orcid.org/0000-0002-0895-3557 https://orcid.org/0000-0002-9703-1780 |
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