Dynamic and specific interaction between synaptic NR2-NMDA receptor and PDZ proteins
The relative content of NR2 subunits in the NMDA receptor confers specific signaling properties and plasticity to synapses. However, the mechanisms that dynamically govern the retention of synaptic NMDARs, in particular 2A-NMDARs, remain poorly understood. Here, we investigate the dynamic interactio...
Main Authors: | Bard, Lucie, Sainlos, Matthieu, Bouchet, Delphine, Cousins, Sarah, Mikasova, Lenka, Breillat, Christelle, Stephenson, F. Anne, Imperiali, Barbara, Choquet, Daniel, Groc, Laurent |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2014
|
Online Access: | http://hdl.handle.net/1721.1/84594 https://orcid.org/0000-0002-5749-7869 |
Similar Items
-
Caged Mono- and Divalent Ligands for Light-Assisted Disruption of PDZ Domain-Mediated Interactions
by: Sainlos, Matthieu, et al.
Published: (2014) -
GluN3A subunit tunes NMDA receptor synaptic trafficking and content during postnatal brain development
by: Inmaculada M. González-González, et al.
Published: (2023-05-01) -
Differential interaction of NMDA receptor subtypes with the post-synaptic density-95 family of membrane associated guanylate kinase proteins.
by: Cousins, S, et al.
Published: (2008) -
A general screening strategy for peptide-based fluorogenic ligands
by: Sainlos, Matthieu, et al.
Published: (2012) -
Monitoring protein interactions and dynamics with solvatochromic fluorophores
by: Loving, Galen S., et al.
Published: (2012)