Continuous flow photocatalysis enhanced using an aluminum mirror: rapid and selective synthesis of 2′-deoxy and 2′,3′-dideoxynucleosides
A unique photochemical flow reactor featuring quartz tubing, an aluminum mirror and temperature control has been developed for the photo-induced electron-transfer deoxygenation reaction to produce 2′-deoxy and 2′,3′-dideoxynucleosides. The continuous flow format significantly increased the efficienc...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Royal Society of Chemistry
2014
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| Online Access: | http://hdl.handle.net/1721.1/84618 https://orcid.org/0000-0002-8601-7799 |
| Summary: | A unique photochemical flow reactor featuring quartz tubing, an aluminum mirror and temperature control has been developed for the photo-induced electron-transfer deoxygenation reaction to produce 2′-deoxy and 2′,3′-dideoxynucleosides. The continuous flow format significantly increased the efficiency and selectivity of the reaction. |
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