Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling

Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling

Many tumors contain heterogeneous populations of cells, only some of which exhibit increased tumorigenicity and resistance to anticancer therapies. Evidence suggests that these aggressive cancer cells, often termed “cancer stem cells” or “cancer stem-like cells” (CSCs), rely upon developmental signa...

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Bibliographic Details
Main Authors: Gupta, Piyush, Fillmore, Christine M., Rudnick, Jenny A., Caballero, Silvia, Keller, Patricia J., Kuperwasser, Charlotte, Lander, Eric Steven
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2014
Online Access:http://hdl.handle.net/1721.1/84629
https://orcid.org/0000-0002-9703-1780

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http://hdl.handle.net/1721.1/84629
https://orcid.org/0000-0002-9703-1780

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