Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling
Many tumors contain heterogeneous populations of cells, only some of which exhibit increased tumorigenicity and resistance to anticancer therapies. Evidence suggests that these aggressive cancer cells, often termed “cancer stem cells” or “cancer stem-like cells” (CSCs), rely upon developmental signa...
Main Authors: | Gupta, Piyush, Fillmore, Christine M., Rudnick, Jenny A., Caballero, Silvia, Keller, Patricia J., Kuperwasser, Charlotte, Lander, Eric Steven |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2014
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Online Access: | http://hdl.handle.net/1721.1/84629 https://orcid.org/0000-0002-9703-1780 |
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