Dual Roles for PARP1 during Heat Shock: Transcriptional Activator and Posttranscriptional Inhibitor of Gene Expression
In this issue of Molecular Cell, Di Giammartino et al. (2012) identify a new function for PARP1 in the post-transcriptional regulation of mRNAs via ADP-ribosylation of poly(A) polymerase, a mRNA 3′ processing enzyme.
Main Authors: | Chang, Paul, Vyas, Sejal |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2014
|
Online Access: | http://hdl.handle.net/1721.1/84646 |
Similar Items
-
Widespread Inhibition of Posttranscriptional Splicing Shapes the Cellular Transcriptome following Heat Shock
by: Shalgi, Reut, et al.
Published: (2015) -
A systematic analysis of the PARP protein family identifies new functions critical for cell physiology
by: Vyas, Sejal, et al.
Published: (2015) -
Farnesylation-dependent regulation of transcripts by PARP13
by: Uchima, Lilen
Published: (2016) -
A combinatorial approach to determine the context-dependent role in transcriptional and posttranscriptional regulation in Arabidopsis Thaliana
by: Lu, Le
Published: (2008) -
Characterization of miR-3099-mediated posttranscriptional of target genes regulation during neurogenesis in mice
by: Zainal Abidin, Shahidee
Published: (2019)