Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli

Individual genetic variation affects gene responsiveness to stimuli, often by influencing complex molecular circuits. Here we combine genomic and intermediate-scale transcriptional profiling with computational methods to identify variants that affect the responsiveness of genes to stimuli (responsiv...

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Bibliographic Details
Main Authors: Gat-Viks, Irit, Chevrier, Nicolas, Wilentzik, Roni, Eisenhaure, Thomas, Raychowdhury, Raktima, Steuerman, Yael, Shalek, Alex K., Hacohen, Nir, Amit, Ido, Regev, Aviv
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2014
Online Access:http://hdl.handle.net/1721.1/84994
https://orcid.org/0000-0001-8567-2049