Antisense RNA polymerase II divergent transcripts are P-TEFb dependent and substrates for the RNA exosome
Divergent transcription occurs at the majority of RNA polymerase II (RNAPII) promoters in mouse embryonic stem cells (mESCs), and this activity correlates with CpG islands. Here we report the characterization of upstream antisense transcription in regions encoding transcription start site associated...
Main Authors: | Flynn, Ryan A., Almada, Albert Ernesto, Zamudio, Jesse Ray, Sharp, Phillip A. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2014
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Online Access: | http://hdl.handle.net/1721.1/85106 https://orcid.org/0000-0003-1465-1691 https://orcid.org/0000-0001-5013-0442 |
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