Allosteric regulation of DegS protease subunits through a shared energy landscape

Allosteric regulation of DegS protease subunits through a shared energy landscape

The PDZ domains of the trimeric DegS protease bind unassembled outer-membrane proteins (OMPs) that accumulate in the Escherichia coli periplasm. This cooperative binding reaction triggers a proteolytic cascade that activates a transcriptional stress response. To dissect the mechanism of allosteric a...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Mauldin, Randall V., Sauer, Robert T
अन्य लेखक:	Massachusetts Institute of Technology. Department of Biology
स्वरूप:	लेख
भाषा:	en_US
प्रकाशित:	Nature Publishing Group 2014
ऑनलाइन पहुंच:	http://hdl.handle.net/1721.1/85173 https://orcid.org/0000-0002-1719-5399

समान संसाधन

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