Spin models inferred from patient-derived viral sequence data faithfully describe HIV fitness landscapes
Mutational escape from vaccine-induced immune responses has thwarted the development of a successful vaccine against AIDS, whose causative agent is HIV, a highly mutable virus. Knowing the virus' fitness as a function of its proteomic sequence can enable rational design of potent vaccines, as t...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
American Physical Society
2014
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| Online Access: | http://hdl.handle.net/1721.1/85205 https://orcid.org/0000-0003-1467-421X https://orcid.org/0000-0003-1268-9602 https://orcid.org/0000-0002-1112-5912 |