Measurement of the Time-Resolved Reflection Matrix for Enhancing Light Energy Delivery into a Scattering Medium
Multiple scatterings occurring in a turbid medium attenuate the intensity of propagating waves. Here, we propose a method to efficiently deliver light energy to the desired target depth in a scattering medium. We measure the time-resolved reflection matrix of a scattering medium using coherent time-...
| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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American Physical Society
2014
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| Online Access: | http://hdl.handle.net/1721.1/85211 https://orcid.org/0000-0003-4698-6488 |
| _version_ | 1826194727296303104 |
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| author | Choi, Youngwoon Hillman, Timothy Robert Choi, Wonjun Lue, Niyom Choi, Wonshik Yaqoob, Zahid Dasari, Ramachandra Rao So, Peter T. C. |
| author2 | Massachusetts Institute of Technology. Department of Biological Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Biological Engineering Choi, Youngwoon Hillman, Timothy Robert Choi, Wonjun Lue, Niyom Choi, Wonshik Yaqoob, Zahid Dasari, Ramachandra Rao So, Peter T. C. |
| author_sort | Choi, Youngwoon |
| collection | MIT |
| description | Multiple scatterings occurring in a turbid medium attenuate the intensity of propagating waves. Here, we propose a method to efficiently deliver light energy to the desired target depth in a scattering medium. We measure the time-resolved reflection matrix of a scattering medium using coherent time-gated detection. From this matrix, we derive and experimentally implement an incident wave pattern that optimizes the detected signal corresponding to a specific arrival time. This leads to enhanced light delivery at the target depth. The proposed method will lay a foundation for efficient phototherapy and deep-tissue in vivo imaging in the near future. |
| first_indexed | 2024-09-23T10:01:12Z |
| format | Article |
| id | mit-1721.1/85211 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T10:01:12Z |
| publishDate | 2014 |
| publisher | American Physical Society |
| record_format | dspace |
| spelling | mit-1721.1/852112022-09-30T18:18:20Z Measurement of the Time-Resolved Reflection Matrix for Enhancing Light Energy Delivery into a Scattering Medium Choi, Youngwoon Hillman, Timothy Robert Choi, Wonjun Lue, Niyom Choi, Wonshik Yaqoob, Zahid Dasari, Ramachandra Rao So, Peter T. C. Massachusetts Institute of Technology. Department of Biological Engineering Massachusetts Institute of Technology. Department of Chemistry Massachusetts Institute of Technology. Department of Mechanical Engineering Massachusetts Institute of Technology. Laser Biomedical Research Center Massachusetts Institute of Technology. Spectroscopy Laboratory Choi, Youngwoon Hillman, Timothy Robert Lue, Niyom Dasari, Ramachandra Rao So, Peter T. C. Yaqoob, Zahid Multiple scatterings occurring in a turbid medium attenuate the intensity of propagating waves. Here, we propose a method to efficiently deliver light energy to the desired target depth in a scattering medium. We measure the time-resolved reflection matrix of a scattering medium using coherent time-gated detection. From this matrix, we derive and experimentally implement an incident wave pattern that optimizes the detected signal corresponding to a specific arrival time. This leads to enhanced light delivery at the target depth. The proposed method will lay a foundation for efficient phototherapy and deep-tissue in vivo imaging in the near future. National Institutes of Health (U.S.) (9P41EB015871-26A10 2014-03-03T16:14:59Z 2014-03-03T16:14:59Z 2013-12 2013-10 Article http://purl.org/eprint/type/JournalArticle 0031-9007 1079-7114 http://hdl.handle.net/1721.1/85211 Choi, Youngwoon, Timothy Hillman, Wonjun Choi, Niyom Lue, Ramachandra Dasari, Peter So, Wonshik Choi, and Zahid Yaqoob. “Measurement of the Time-Resolved Reflection Matrix for Enhancing Light Energy Delivery into a Scattering Medium.” Physical Review Letters 111, no. 24 (December 2013). © 2013 American Physical Society https://orcid.org/0000-0003-4698-6488 en_US http://dx.doi.org/10.1103/PhysRevLett.111.243901 Physical Review Letters Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf American Physical Society American Physical Society |
| spellingShingle | Choi, Youngwoon Hillman, Timothy Robert Choi, Wonjun Lue, Niyom Choi, Wonshik Yaqoob, Zahid Dasari, Ramachandra Rao So, Peter T. C. Measurement of the Time-Resolved Reflection Matrix for Enhancing Light Energy Delivery into a Scattering Medium |
| title | Measurement of the Time-Resolved Reflection Matrix for Enhancing Light Energy Delivery into a Scattering Medium |
| title_full | Measurement of the Time-Resolved Reflection Matrix for Enhancing Light Energy Delivery into a Scattering Medium |
| title_fullStr | Measurement of the Time-Resolved Reflection Matrix for Enhancing Light Energy Delivery into a Scattering Medium |
| title_full_unstemmed | Measurement of the Time-Resolved Reflection Matrix for Enhancing Light Energy Delivery into a Scattering Medium |
| title_short | Measurement of the Time-Resolved Reflection Matrix for Enhancing Light Energy Delivery into a Scattering Medium |
| title_sort | measurement of the time resolved reflection matrix for enhancing light energy delivery into a scattering medium |
| url | http://hdl.handle.net/1721.1/85211 https://orcid.org/0000-0003-4698-6488 |
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