Identification of the Cdc48•20S Proteasome as an Ancient AAA+ Proteolytic Machine
Proteasomes are the major energy-dependent proteolytic machines in the eukaryotic and archaeal domains of life. To execute protein degradation, the 20S core peptidase combines with the AAA+ ring of the 19S regulatory particle in eukarya or with the AAA+ proteasome-activating nucleotidase ring in som...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
American Association for the Advancement of Science
2014
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| Online Access: | http://hdl.handle.net/1721.1/85559 https://orcid.org/0000-0002-1719-5399 |