Apical domain polarization localizes actin–myosin activity to drive ratchet-like apical constriction
Apical constriction promotes epithelia folding, which changes tissue architecture. During Drosophila gastrulation, mesoderm cells exhibit repeated contractile pulses that are stabilized such that cells apically constrict like a ratchet. The transcription factor Twist is required to stabilize cell sh...
Main Authors: | Tworoger, Michael B., Martin, Adam C, Mason, Frank M |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2014
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Online Access: | http://hdl.handle.net/1721.1/85570 https://orcid.org/0000-0001-8060-2607 https://orcid.org/0000-0003-1338-494X |
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