Defining the expression hierarchy of latent T-cell epitopes in Epstein-Barr virus infection with TCR-like antibodies

Defining the expression hierarchy of latent T-cell epitopes in Epstein-Barr virus infection with TCR-like antibodies

Epstein-Barr virus (EBV) is a gamma herpesvirus that causes a life-long latent infection in human hosts. The latent gene products LMP1, LMP2A and EBNA1 are expressed by EBV-associated tumors and peptide epitopes derived from these can be targeted by CD8 Cytotoxic T-Lymphocyte (CTL) lines. Whilst CTL...

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Bibliographic Details
Main Authors: Sim, Adrian Chong Nyi, Too, Chien Tei, Oo, Min Zin, Lai, Junyun, Eio, Michelle Yating, Song, Zhenying, Srinivasan, Nalini, Tan, Diane Ai Lin, Pang, Shyue Wei, Gan, Shu Uin, Lee, Kok Onn, Loh, Thomas Kwok Seng, Chen, Jianzhu, Chan, Soh Ha, MacAry, Paul Anthony
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2014
Online Access:http://hdl.handle.net/1721.1/85918
https://orcid.org/0000-0002-5687-6154

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