Quantifying Missing Heritability at Known GWAS Loci

Recent work has shown that much of the missing heritability of complex traits can be resolved by estimates of heritability explained by all genotyped SNPs. However, it is currently unknown how much heritability is missing due to poor tagging or additional causal variants at known GWAS loci. Here, we...

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Main Authors: Gusev, Alexander, Bhatia, Gaurav, Zaitlen, Noah, Vilhjalmsson, Bjarni J., Diogo, Dorothee, Stahl, Eli A., Gregersen, Peter K., Worthington, Jane, Klareskog, Lars, Raychaudhuri, Soumya, Plenge, Robert M., Pasaniuc, Bogdan, Price, Alkes L.
其他作者: Whitaker College of Health Sciences and Technology
格式: 文件
语言:en_US
出版: Public Library of Science 2014
在线阅读:http://hdl.handle.net/1721.1/86014

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