Identification of apolipoprotein D as a cardioprotective gene using a mouse model of lethal atherosclerotic coronary artery disease

Identification of apolipoprotein D as a cardioprotective gene using a mouse model of lethal atherosclerotic coronary artery disease

Mice with homozygous null mutations in the HDL receptor (scavenger receptor class B, type I, or SR-BI) and apolipoprotein E (apoE) genes [SR-BI/apoE double KO (SR-BI[superscript −/−]/apoE[superscript −/−] or dKO) mice] spontaneously develop occlusive, atherosclerotic coronary artery disease (CAD) an...

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Bibliographic Details
Main Authors: Mani, D. R., Tsukamoto, Kosuke, Zhang, Songwen, Krieger, Monty, Shi, Jianru, Haagensen, Darrow E., Otsuka, Fumiyuki, Guan, Jian, Smith, Jonathan D., Weng, Wei, Liao, Ronglih, Kolodgie, Frank D., Virmani, Renu
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2014
Online Access:http://hdl.handle.net/1721.1/86062
https://orcid.org/0000-0003-4541-5181

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