Counter-Driven Regression for Label Inference in Atlas-Based Segmentation

We present a novel method for inferring tissue labels in atlas-based image segmentation using Gaussian process regression. Atlas-based segmentation results in probabilistic label maps that serve as input to our method. We introduce a contour-driven prior distribution over label maps to incorporate i...

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Main Authors: Wachinger, Christian, Sharp, Gregory C., Golland, Polina
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Springer-Verlag 2014
Online Access:http://hdl.handle.net/1721.1/86193
https://orcid.org/0000-0002-3652-1874
https://orcid.org/0000-0003-2516-731X
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author Wachinger, Christian
Sharp, Gregory C.
Golland, Polina
author2 Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
author_facet Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Wachinger, Christian
Sharp, Gregory C.
Golland, Polina
author_sort Wachinger, Christian
collection MIT
description We present a novel method for inferring tissue labels in atlas-based image segmentation using Gaussian process regression. Atlas-based segmentation results in probabilistic label maps that serve as input to our method. We introduce a contour-driven prior distribution over label maps to incorporate image features of the input scan into the label inference problem. The mean function of the Gaussian process posterior distribution yields the MAP estimate of the label map and is used in the subsequent voting. We demonstrate improved segmentation accuracy when our approach is combined with two different patch-based segmentation techniques. We focus on the segmentation of parotid glands in CT scans of patients with head and neck cancer, which is important for radiation therapy planning.
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spelling mit-1721.1/861932023-05-17T18:54:04Z Counter-Driven Regression for Label Inference in Atlas-Based Segmentation Wachinger, Christian Sharp, Gregory C. Golland, Polina Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Wachinger, Christian Golland, Polina We present a novel method for inferring tissue labels in atlas-based image segmentation using Gaussian process regression. Atlas-based segmentation results in probabilistic label maps that serve as input to our method. We introduce a contour-driven prior distribution over label maps to incorporate image features of the input scan into the label inference problem. The mean function of the Gaussian process posterior distribution yields the MAP estimate of the label map and is used in the subsequent voting. We demonstrate improved segmentation accuracy when our approach is combined with two different patch-based segmentation techniques. We focus on the segmentation of parotid glands in CT scans of patients with head and neck cancer, which is important for radiation therapy planning. National Alliance for Medical Image Computing (U.S.) (NIH NIBIB NAMIC U54-EB005149) Neuroimaging Analysis Center (U.S.) (NIH NCRR NAC P41-RR13218) Neuroimaging Analysis Center (U.S.) (NIH NIBIB NAC P41-EB-015902) 2014-04-17T13:57:28Z 2014-04-17T13:57:28Z 2013-09 Article http://purl.org/eprint/type/ConferencePaper 978-3-642-40759-8 978-3-642-40760-4 0302-9743 http://hdl.handle.net/1721.1/86193 Wachinger, Christian, Gregory C. Sharp, and Polina Golland. “Contour-Driven Regression for Label Inference in Atlas-Based Segmentation.” Medical Image Computing and Computer-Assisted Intervention – MICCAI 2013. Ed. Kensaku Mori et al. Vol. 8151. Springer Berlin Heidelberg, 2013. 211–218. Lecture Notes in Computer Science. https://orcid.org/0000-0002-3652-1874 https://orcid.org/0000-0003-2516-731X en_US http://dx.doi.org/10.1007/978-3-642-40760-4_27 Medical Image Computing and Computer-Assisted Intervention – MICCAI 2013 application/pdf Springer-Verlag Wachinger
spellingShingle Wachinger, Christian
Sharp, Gregory C.
Golland, Polina
Counter-Driven Regression for Label Inference in Atlas-Based Segmentation
title Counter-Driven Regression for Label Inference in Atlas-Based Segmentation
title_full Counter-Driven Regression for Label Inference in Atlas-Based Segmentation
title_fullStr Counter-Driven Regression for Label Inference in Atlas-Based Segmentation
title_full_unstemmed Counter-Driven Regression for Label Inference in Atlas-Based Segmentation
title_short Counter-Driven Regression for Label Inference in Atlas-Based Segmentation
title_sort counter driven regression for label inference in atlas based segmentation
url http://hdl.handle.net/1721.1/86193
https://orcid.org/0000-0002-3652-1874
https://orcid.org/0000-0003-2516-731X
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AT sharpgregoryc counterdrivenregressionforlabelinferenceinatlasbasedsegmentation
AT gollandpolina counterdrivenregressionforlabelinferenceinatlasbasedsegmentation