Ultrahigh speed endoscopic optical coherence tomography using micro-motor imaging catheter and VCSEL technology

We developed a micro-motor based miniature catheter with an outer diameter of 3mm for ultrahigh speed endoscopic optical coherence tomography (OCT) using vertical cavity surface-emitting laser (VCSEL) at a 1MHz axial scan rate. The micro-motor can rotate a micro-prism at 1,200-72,000rpm (correspondi...

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Main Authors: Tsai, Tsung-Han, Tao, Yuankai K., Potsaid, Benjamin M., Jayaraman, Vijaysekhar, Kraus, Martin Franz Georg, Heim, Peter J. S., Hornegger, Joachim, Mashimo, Hiroshi, Cable, Alex E., Fujimoto, James G.
Other Authors: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Format: Article
Language:en_US
Published: SPIE 2014
Online Access:http://hdl.handle.net/1721.1/86220
https://orcid.org/0000-0002-0828-4357
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author Tsai, Tsung-Han
Tao, Yuankai K.
Potsaid, Benjamin M.
Jayaraman, Vijaysekhar
Kraus, Martin Franz Georg
Heim, Peter J. S.
Hornegger, Joachim
Mashimo, Hiroshi
Cable, Alex E.
Fujimoto, James G.
author2 Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
author_facet Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Tsai, Tsung-Han
Tao, Yuankai K.
Potsaid, Benjamin M.
Jayaraman, Vijaysekhar
Kraus, Martin Franz Georg
Heim, Peter J. S.
Hornegger, Joachim
Mashimo, Hiroshi
Cable, Alex E.
Fujimoto, James G.
author_sort Tsai, Tsung-Han
collection MIT
description We developed a micro-motor based miniature catheter with an outer diameter of 3mm for ultrahigh speed endoscopic optical coherence tomography (OCT) using vertical cavity surface-emitting laser (VCSEL) at a 1MHz axial scan rate. The micro-motor can rotate a micro-prism at 1,200-72,000rpm (corresponding to 20- 1,200fps) with less than 5V driving voltage to provide fast and stable scanning, which is not sensitive to the bending of the catheter. The side-viewing probe can be pulled back for a long distance to acquire three-dimensional (3D) dataset covering a large area on the specimen. VCSEL provides high a-line rate to support dense sampling under high frame rate operation. With the use of a C++ based high speed data acquisition (DAQ) system, in vivo three-dimensional OCT imaging in rabbit GI tract with 1.6mm depth range, 11μm axial resolution, 8μm lateral resolution, and frame rate of 400fps is demonstrated.
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spelling mit-1721.1/862202022-09-28T16:39:58Z Ultrahigh speed endoscopic optical coherence tomography using micro-motor imaging catheter and VCSEL technology Tsai, Tsung-Han Tao, Yuankai K. Potsaid, Benjamin M. Jayaraman, Vijaysekhar Kraus, Martin Franz Georg Heim, Peter J. S. Hornegger, Joachim Mashimo, Hiroshi Cable, Alex E. Fujimoto, James G. Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology. Research Laboratory of Electronics Tsai, Tsung-Han Tao, Yuankai K. Potsaid, Benjamin M. Kraus, Martin Franz Georg Fujimoto, James G. We developed a micro-motor based miniature catheter with an outer diameter of 3mm for ultrahigh speed endoscopic optical coherence tomography (OCT) using vertical cavity surface-emitting laser (VCSEL) at a 1MHz axial scan rate. The micro-motor can rotate a micro-prism at 1,200-72,000rpm (corresponding to 20- 1,200fps) with less than 5V driving voltage to provide fast and stable scanning, which is not sensitive to the bending of the catheter. The side-viewing probe can be pulled back for a long distance to acquire three-dimensional (3D) dataset covering a large area on the specimen. VCSEL provides high a-line rate to support dense sampling under high frame rate operation. With the use of a C++ based high speed data acquisition (DAQ) system, in vivo three-dimensional OCT imaging in rabbit GI tract with 1.6mm depth range, 11μm axial resolution, 8μm lateral resolution, and frame rate of 400fps is demonstrated. United States. Air Force Office of Scientific Research (contract FA9550-10-1-0063) United States. Air Force Office of Scientific Research (contract FA9550-10-1-0551) National Institutes of Health (U.S.) (R01-CA075289-15) National Institutes of Health (U.S.) (R44CA101067-06) National Institutes of Health (U.S.) (R01-EY011289-24) National Institutes of Health (U.S.) (R01-NS057476-02) National Institutes of Health (U.S.) (R01EY013516-16) Deutsche Forschungsgemeinschaft (DFG-GSC80-SAOT) 2014-04-23T19:07:08Z 2014-04-23T19:07:08Z 2013-03 Article http://purl.org/eprint/type/JournalArticle 9780819493408 0819493406 http://hdl.handle.net/1721.1/86220 Tsai, Tsung-Han, Yuankai K. Tao, Benjamin M. Potsaid, Vijaysekhar Jayaraman, Martin F. Kraus, Peter J. S. Heim, Joachim Hornegger, Hiroshi Mashimo, Alex E. Cable, and James G. Fujimoto. “Ultrahigh Speed Endoscopic Optical Coherence Tomography Using Micro-Motor Imaging Catheter and VCSEL Technology.” Edited by James G. Fujimoto, Joseph A. Izatt, and Valery V. Tuchin. Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII (March 20, 2013). (SPIE proceedings; Vol. 8571). https://orcid.org/0000-0002-0828-4357 en_US http://dx.doi.org/10.1117/12.2006952 Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf SPIE SPIE
spellingShingle Tsai, Tsung-Han
Tao, Yuankai K.
Potsaid, Benjamin M.
Jayaraman, Vijaysekhar
Kraus, Martin Franz Georg
Heim, Peter J. S.
Hornegger, Joachim
Mashimo, Hiroshi
Cable, Alex E.
Fujimoto, James G.
Ultrahigh speed endoscopic optical coherence tomography using micro-motor imaging catheter and VCSEL technology
title Ultrahigh speed endoscopic optical coherence tomography using micro-motor imaging catheter and VCSEL technology
title_full Ultrahigh speed endoscopic optical coherence tomography using micro-motor imaging catheter and VCSEL technology
title_fullStr Ultrahigh speed endoscopic optical coherence tomography using micro-motor imaging catheter and VCSEL technology
title_full_unstemmed Ultrahigh speed endoscopic optical coherence tomography using micro-motor imaging catheter and VCSEL technology
title_short Ultrahigh speed endoscopic optical coherence tomography using micro-motor imaging catheter and VCSEL technology
title_sort ultrahigh speed endoscopic optical coherence tomography using micro motor imaging catheter and vcsel technology
url http://hdl.handle.net/1721.1/86220
https://orcid.org/0000-0002-0828-4357
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