High-Frequency, Long-Range Coupling Between Prefrontal and Visual Cortex During Attention
Electrical recordings in humans and monkeys show attentional enhancement of evoked responses and gamma synchrony in ventral stream cortical areas. Does this synchrony result from intrinsic activity in visual cortex or from inputs from other structures? Using paired recordings in the frontal eye fiel...
| Main Authors: | , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
American Association for the Advancement of Science (AAAS)
2014
|
| Online Access: | http://hdl.handle.net/1721.1/86394 https://orcid.org/0000-0003-3466-8706 https://orcid.org/0000-0002-5938-4227 |
| _version_ | 1826194645928902656 |
|---|---|
| author | Gregoriou, Georgia G. Zhou, Huihui Desimone, Robert Gotts, Stephen J. |
| author2 | McGovern Institute for Brain Research at MIT |
| author_facet | McGovern Institute for Brain Research at MIT Gregoriou, Georgia G. Zhou, Huihui Desimone, Robert Gotts, Stephen J. |
| author_sort | Gregoriou, Georgia G. |
| collection | MIT |
| description | Electrical recordings in humans and monkeys show attentional enhancement of evoked responses and gamma synchrony in ventral stream cortical areas. Does this synchrony result from intrinsic activity in visual cortex or from inputs from other structures? Using paired recordings in the frontal eye field (FEF) and area V4, we found that attention to a stimulus in their joint receptive field leads to enhanced oscillatory coupling between the two areas, particularly at gamma frequencies. This coupling appeared to be initiated by FEF and was time-shifted by about 8 to 13 milliseconds across a range of frequencies. Considering the expected conduction and synaptic delays between the areas, this time-shifted coupling at gamma frequencies may optimize the postsynaptic impact of spikes from one area upon the other, improving cross-area communication with attention. |
| first_indexed | 2024-09-23T09:59:11Z |
| format | Article |
| id | mit-1721.1/86394 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T09:59:11Z |
| publishDate | 2014 |
| publisher | American Association for the Advancement of Science (AAAS) |
| record_format | dspace |
| spelling | mit-1721.1/863942022-09-30T18:08:31Z High-Frequency, Long-Range Coupling Between Prefrontal and Visual Cortex During Attention Gregoriou, Georgia G. Zhou, Huihui Desimone, Robert Gotts, Stephen J. McGovern Institute for Brain Research at MIT Gregoriou, Georgia G. Zhou, Huihui Desimone, Robert Electrical recordings in humans and monkeys show attentional enhancement of evoked responses and gamma synchrony in ventral stream cortical areas. Does this synchrony result from intrinsic activity in visual cortex or from inputs from other structures? Using paired recordings in the frontal eye field (FEF) and area V4, we found that attention to a stimulus in their joint receptive field leads to enhanced oscillatory coupling between the two areas, particularly at gamma frequencies. This coupling appeared to be initiated by FEF and was time-shifted by about 8 to 13 milliseconds across a range of frequencies. Considering the expected conduction and synaptic delays between the areas, this time-shifted coupling at gamma frequencies may optimize the postsynaptic impact of spikes from one area upon the other, improving cross-area communication with attention. Grant EY017292 Grant EY17921 2014-05-02T19:39:28Z 2014-05-02T19:39:28Z 2009-05 2009-01 Article http://purl.org/eprint/type/JournalArticle 0036-8075 1095-9203 http://hdl.handle.net/1721.1/86394 Gregoriou, G. G., S. J. Gotts, H. Zhou, and R. Desimone. “High-Frequency, Long-Range Coupling Between Prefrontal and Visual Cortex During Attention.” Science 324, no. 5931 (May 29, 2009): 1207–1210. https://orcid.org/0000-0003-3466-8706 https://orcid.org/0000-0002-5938-4227 en_US http://dx.doi.org/10.1126/science.1171402 Science Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf American Association for the Advancement of Science (AAAS) PMC |
| spellingShingle | Gregoriou, Georgia G. Zhou, Huihui Desimone, Robert Gotts, Stephen J. High-Frequency, Long-Range Coupling Between Prefrontal and Visual Cortex During Attention |
| title | High-Frequency, Long-Range Coupling Between Prefrontal and Visual Cortex During Attention |
| title_full | High-Frequency, Long-Range Coupling Between Prefrontal and Visual Cortex During Attention |
| title_fullStr | High-Frequency, Long-Range Coupling Between Prefrontal and Visual Cortex During Attention |
| title_full_unstemmed | High-Frequency, Long-Range Coupling Between Prefrontal and Visual Cortex During Attention |
| title_short | High-Frequency, Long-Range Coupling Between Prefrontal and Visual Cortex During Attention |
| title_sort | high frequency long range coupling between prefrontal and visual cortex during attention |
| url | http://hdl.handle.net/1721.1/86394 https://orcid.org/0000-0003-3466-8706 https://orcid.org/0000-0002-5938-4227 |
| work_keys_str_mv | AT gregoriougeorgiag highfrequencylongrangecouplingbetweenprefrontalandvisualcortexduringattention AT zhouhuihui highfrequencylongrangecouplingbetweenprefrontalandvisualcortexduringattention AT desimonerobert highfrequencylongrangecouplingbetweenprefrontalandvisualcortexduringattention AT gottsstephenj highfrequencylongrangecouplingbetweenprefrontalandvisualcortexduringattention |