The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse

The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse

The histone-modifying complexes PRC2 and TrxG/MLL play pivotal roles in determining the activation state of genes controlling pluripotency, lineage commitment, and cell differentiation. Long noncoding RNAs (lncRNAs) can bind to either complex, and some have been shown to act as modulators of PRC2 or...

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Bibliographic Details
Main Authors: Grote, Phillip, Wittler, Lars, Hendrix, David A., Koch, Frederic, Beisaw, Arica, Macura, Karol, Kellis, Manolis, Werber, Martin, Herrmann, Bernhard G., Wahrisch, Sandra, Blass, Gaby
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/87007

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