Linking DNA Methyltransferases to Epigenetic Marks and Nucleosome Structure Genome-wide in Human Tumor Cells
DNA methylation, mediated by the combined action of three DNA methyltransferases (DNMT1, DNMT3A, and DNMT3B), is essential for mammalian development and is a major contributor to cellular transformation. To elucidate how DNA methylation is targeted, we mapped the genome-wide localization of all DNMT...
Main Authors: | Jin, Bilian, Ernst, Jason, Tiedemann, Rochelle L., Xu, Hongyan, Sureshchandra, Suhas, Kellis, Manolis, Dalton, Stephen, Liu, Chen, Choi, Jeong-Hyeon, Robertson, Keith D. |
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Other Authors: | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2014
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Online Access: | http://hdl.handle.net/1721.1/87008 |
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