Three Periods of Regulatory Innovation During Vertebrate Evolution

Three Periods of Regulatory Innovation During Vertebrate Evolution

The gain, loss, and modification of gene regulatory elements may underlie a substantial proportion of phenotypic changes on animal lineages. To investigate the gain of regulatory elements throughout vertebrate evolution, we identified genome-wide sets of putative regulatory regions for five vertebra...

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Bibliographic Details
Main Authors: Kellis, Manolis, Lowe, Craig B., Siepel, Adam, Raney, Brian J., Clamp, Michele, Salama, Sofie R., Kingsley, David M., Lindblad-Toh, Kerstin, Haussler, David
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2014
Online Access:http://hdl.handle.net/1721.1/87017

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