Computational analysis of noncoding RNAs
Noncoding RNAs have emerged as important key players in the cell. Understanding their surprisingly diverse range of functions is challenging for experimental and computational biology. Here, we review computational methods to analyze noncoding RNAs. The topics covered include basic and advanced tech...
| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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John Wiley & Sons, Inc
2014
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| Online Access: | http://hdl.handle.net/1721.1/87066 https://orcid.org/0000-0002-2724-7228 |
| _version_ | 1811091016949694464 |
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| author | Washietl, Stefan Will, Sebastian Hendrix, David A. Goff, Loyal Rinn, John L. Berger, Bonnie Kellis, Manolis |
| author2 | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
| author_facet | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory Washietl, Stefan Will, Sebastian Hendrix, David A. Goff, Loyal Rinn, John L. Berger, Bonnie Kellis, Manolis |
| author_sort | Washietl, Stefan |
| collection | MIT |
| description | Noncoding RNAs have emerged as important key players in the cell. Understanding their surprisingly diverse range of functions is challenging for experimental and computational biology. Here, we review computational methods to analyze noncoding RNAs. The topics covered include basic and advanced techniques to predict RNA structures, annotation of noncoding RNAs in genomic data, mining RNA-seq data for novel transcripts and prediction of transcript structures, computational aspects of microRNAs, and database resources. |
| first_indexed | 2024-09-23T14:55:32Z |
| format | Article |
| id | mit-1721.1/87066 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T14:55:32Z |
| publishDate | 2014 |
| publisher | John Wiley & Sons, Inc |
| record_format | dspace |
| spelling | mit-1721.1/870662022-09-29T11:27:00Z Computational analysis of noncoding RNAs Washietl, Stefan Will, Sebastian Hendrix, David A. Goff, Loyal Rinn, John L. Berger, Bonnie Kellis, Manolis Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology. Department of Mathematics Washietl, Stefan Will, Sebastian Hendrix, David A. Goff, Loyal Berger, Bonnie Kellis, Manolis Noncoding RNAs have emerged as important key players in the cell. Understanding their surprisingly diverse range of functions is challenging for experimental and computational biology. Here, we review computational methods to analyze noncoding RNAs. The topics covered include basic and advanced techniques to predict RNA structures, annotation of noncoding RNAs in genomic data, mining RNA-seq data for novel transcripts and prediction of transcript structures, computational aspects of microRNAs, and database resources. Austrian Science Fund (Schrodinger Fellowship J2966-B12) German Research Foundation (grant WI 3628/1-1 to SW) National Institutes of Health (U.S.) (NIH award 1RC1CA147187) 2014-05-21T18:32:50Z 2014-05-21T18:32:50Z 2012-11 Article http://purl.org/eprint/type/JournalArticle 17577004 http://hdl.handle.net/1721.1/87066 Washietl, Stefan, Sebastian Will, David A. Hendrix, Loyal A. Goff, John L. Rinn, Bonnie Berger, and Manolis Kellis. “Computational Analysis of Noncoding RNAs.” WIREs RNA 3, no. 6 (November 2012): 759–778. https://orcid.org/0000-0002-2724-7228 en_US http://dx.doi.org/10.1002/wrna.1134 Wiley Interdisciplinary Reviews: RNA Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf John Wiley & Sons, Inc PMC |
| spellingShingle | Washietl, Stefan Will, Sebastian Hendrix, David A. Goff, Loyal Rinn, John L. Berger, Bonnie Kellis, Manolis Computational analysis of noncoding RNAs |
| title | Computational analysis of noncoding RNAs |
| title_full | Computational analysis of noncoding RNAs |
| title_fullStr | Computational analysis of noncoding RNAs |
| title_full_unstemmed | Computational analysis of noncoding RNAs |
| title_short | Computational analysis of noncoding RNAs |
| title_sort | computational analysis of noncoding rnas |
| url | http://hdl.handle.net/1721.1/87066 https://orcid.org/0000-0002-2724-7228 |
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