Photosensitizer delivery to vulnerable atherosclerotic plaque: comparison of macrophage-targeted conjugate versus free chlorine(e6)

Photosensitizer delivery to vulnerable atherosclerotic plaque: comparison of macrophage-targeted conjugate versus free chlorine(e6)

We have previously shown that a conjugate (MA-ce6) between maleylated serum albumin and the photosensitizer chlorin(e6) (ce6) is targeted in vitro to macrophages via class A scavenger receptors. We now report on the ability of this conjugate to localize in macrophage-rich atherosclerotic plaques in...

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Bibliographic Details
Main Authors: Tawakol, Ahmed, Castano, Ana P., Anatelli, Florencia, Bashian, Gregory, Stern, Jeremy, Zahra, Touqir, Gad, Faten, Chirico, Stephanie, Ahmadi, Atosa, Fischman, Alan J., Muller, James E., Hamblin, Michael R.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: SPIE 2014
Online Access:http://hdl.handle.net/1721.1/87656

Internet

http://hdl.handle.net/1721.1/87656

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