3' UTR-isoform choice has limited influence on the stability and translational efficiency of most mRNAs in mouse fibroblasts
Variation in protein output across the genome is controlled at several levels, but the relative contributions of different regulatory mechanisms remain poorly understood. Here, we obtained global measurements of decay and translation rates for mRNAs with alternative 3′ untranslated regions (3′ UTRs)...
Main Authors: | Spies, Noah, Bartel, David, Burge, Christopher B |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
Cold Spring Harbor Laboratory Press
2014
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Online Access: | http://hdl.handle.net/1721.1/87993 https://orcid.org/0000-0002-3872-2856 |
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