Quantitative-Proteomic Comparison of Alpha and Beta Cells to Uncover Novel Targets for Lineage Reprogramming
Type-1 diabetes (T1D) is an autoimmune disease in which insulin-secreting pancreatic beta cells are destroyed by the immune system. An emerging strategy to regenerate beta-cell mass is through transdifferentiation of pancreatic alpha cells to beta cells. We previously reported two small molecules, B...
Main Authors: | Choudhary, Amit, Hu He, Kaihui, Mertins, Philipp, Udeshi, Namrata D., Dancik, Vlado, Fomina-Yadlin, Dina, Kubicek, Stefan, Clemons, Paul A., Schreiber, Stuart L., Wagner, Bridget K., Carr, Steven A |
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Other Authors: | Koch Institute for Integrative Cancer Research at MIT |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2014
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Online Access: | http://hdl.handle.net/1721.1/88043 https://orcid.org/0000-0002-7203-4299 |
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