The Enigmatic Conservation of a Rap1 Binding Site in the Saccharomyces cerevisiae HMR-E Silencer

Silencing at the HMR and HML loci in Saccharomyces cerevisiae requires recruitment of Sir proteins to the HML and HMR silencers. The silencers are regulatory sites flanking both loci and consisting of binding sites for the Rap1, Abf1, and ORC proteins, each of which also functions at hundreds of sit...

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Bibliographic Details
Main Authors: Teytelman, Leonid, Nishimura, Erin A. Osborne, Ozaydin, Bilge, Eisen, Michael B., Rine, Jasper
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Genetics Society of America 2014
Online Access:http://hdl.handle.net/1721.1/88113