Rosa26-GFP Direct Repeat (RaDR-GFP) Mice Reveal Tissue- and Age-Dependence of Homologous Recombination in Mammals In Vivo

Homologous recombination (HR) is critical for the repair of double strand breaks and broken replication forks. Although HR is mostly error free, inherent or environmental conditions that either suppress or induce HR cause genomic instability. Despite its importance in carcinogenesis, due to limitati...

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Bibliographic Details
Main Authors: Sukup-Jackson, Michelle R., Kiraly, Orsolya, Na, Li, Rowland, Elizabeth A., Winther, Kelly E., Chow, Danielle N., Kimoto, Takafumi, Matsuguchi, Tetsuya, Jonnalagadda, Vidya S., Maklakova, Vilena I., Singh, Vijay R., Wadduwage, Dushan N., Rajapakse, Jagath, So, Peter T. C., Collier, Lara S., Engelward, Bevin P., Kay, Jennifer Elizabeth
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Public Library of Science 2014
Online Access:http://hdl.handle.net/1721.1/88118
https://orcid.org/0000-0001-5891-0689
https://orcid.org/0000-0003-4698-6488