p53 null Fluorescent Yellow Direct Repeat (FYDR) mice have normal levels of homologous recombination
The tumor suppressor p53 is a transcription factor whose function is critical for maintaining genomic stability in mammalian cells. In response to DNA damage, p53 initiates a signaling cascade that results in cell cycle arrest, DNA repair or, if the damage is severe, programmed cell death. In additi...
| Hauptverfasser: | , , , , |
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| Format: | Artikel |
| Sprache: | en_US |
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Elsevier B.V.
2014
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| Online Zugang: | http://hdl.handle.net/1721.1/88709 |